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BMI and Basal Metabolic Rate Calculator

Find out your BMI and basal calorie expenditure — and understand how your cells convert nutrients into energy, molecule by molecule.

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The biology behind the numbers

🔬 What is the basal metabolic rate?

The basal metabolic rate (BMR) is the minimum amount of energy the body needs to sustain vital functions at complete rest: heartbeat, breathing, body temperature, protein synthesis and continuous cell repair.

It accounts for 60–75% of the total energy expenditure of a sedentary person. Factors such as muscle mass, age and thyroid hormones directly influence this value.

Liver
27%
Brain
19%
Muscles
18%
Kidneys
10%
Heart
7%
Others
19%

⚡ ATP — The Cell’s Energy Currency

ATP (adenosine triphosphate) is the molecule that carries energy inside every cell. When a phosphate bond is broken (ATP → ADP + Pᵢ), it releases ~30.5 kJ/mol that powers molecular motors, ion pumps and protein synthesis.

ATP is not stored in large amounts — it is continuously regenerated by the mitochondria from the nutrients you eat. At rest, the body recycles an amount of ATP equal to its own body weight per day.

🌀 Cellular Respiration — How Cells Convert Food into ATP

Cellular respiration is the set of reactions that turns glucose (and other nutrients) into ATP. It happens in three interdependent stages, the last two inside the mitochondrion — the organelle you can see in the Interphase Simulator.

Glycolysis
Cytoplasm
2
net ATP
→
Pyruvate → Acetyl-CoA
Mito. membrane
—
2 NADH
→
Krebs cycle
Mito. matrix
2
ATP + NADH + FADH₂
→
Oxidative phosphorylation
Inner mito. membrane
28–32
ATP via H⁺ gradient

A single glucose molecule (C₆H₁₂O₆) yields between 30 and 32 ATP molecules after going through all the stages. Most of it comes from oxidative phosphorylation, where the proton (H⁺) gradient built across the inner mitochondrial membrane drives ATP synthase — a molecular nanomotor that spins at ~9,000 rpm.

🍎 Macronutrients and Cellular Energy

Each macronutrient enters cellular respiration through a different route:

Carbohydrates are converted into glucose and go straight into glycolysis — the fastest way to produce ATP.

Fats go through β-oxidation, generating Acetyl-CoA that feeds the Krebs cycle. They yield ~9 kcal/g (double the carbohydrates), which is why they are the main fuel in low-intensity activity.

Proteins are used for energy only as a last resort: their amino acids are converted into Krebs cycle intermediates or into glucose (gluconeogenesis), but their primary role is structural.

📊 Why is every BMR different?

Muscle mass: muscle burns ~13 kcal/kg/day at rest, while fat burns only ~4.5 kcal/kg/day. More muscle means a higher BMR.

Age: BMR drops ~2% per decade after age 20, reflecting the gradual loss of muscle mass and reduced mitochondrial activity.

Hormones: T3 and T4 (thyroid hormones) directly regulate the rate of metabolic reactions in every cell. Hypothyroidism can lower BMR by up to 40%.

Body temperature: a 1 °C fever raises basal metabolism by ~10–13% — cells speed up to fight the infection.

⚠️ The values are educational estimates based on the Mifflin-St Jeor equation. For an individualized nutritional assessment, consult a registered dietitian.

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